1160247-07-3

Excellent regio- and stereoselectivity during nitrile addition to dienylium-Fe(CO)3 can be achieved with perchlorate salts, allowing the preparation of the 1-oxo- and 3-oxo-2-azaspiro[5.5]undecane ring systems[1]. tert-Butyl 3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate has similar structure.

[1] Tricarbonylcyclohexadienyliumiron Complexes in the Synthesis of 2-Azaspiro[5.5]undecane System with Tunable Amide. J. Org. Chem. 1996, 61, 12, 3996–3998. DOI:10.1021/jo9520755