Chemical Properties
colourless to yellow liquid
Uses
Hydroxyacetone is a chemical reagent used in various organic chemical reactions. It is a component of the Mannich reaction, amino acid caalyzes direct asymmetric aldol reactions. In the pharmaceutical
setting, this compound is used in the synthesis of imidazoles acting as potent and orally active antihypertensive agents.
Uses
Hydroxyacetone is used as a reagent in organic chemical reactions. It also serves as a component for Mannich reaction and aldol reactions. It is also used in the syntheses of 2-oxo-propionaldehyde, imidazoles, polyols, acrolein, dyes and skin tanning agents. It yields (R)-1,2-propanediol upon reduction of hydroxyacetone in the presence of a microbial cell catalyst.
Uses
Reagent in organic synthesis; protecting group for the synthesis of peptides.
Definition
ChEBI: A propanone that is acetone in which one of the methyl hydrogens is replaced by a hydroxy group.
General Description
Hydroxyacetone (Acetol) is important for the manufacture of polyols, acrolein, dyes and skin tanning agents. It undergoes asymmetric reduction to yield (R)-1,2-propanediol in the presence of microbial cell catalyst.
Synthesis
from Bromoacetone plus sodium formate, followed by Methanol hydrolysis of the formed ester. Or by biochemical synthesis from Propylene glycol with sorbose bacterium.
storage
4°C, stored under nitroge
