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Boc-Val-Arg-AMC is a synthetic peptide compound. As a specific fluorescent substrate, Boc-Val-Arg-AMC can be specifically cleaved by specific enzymes, especially thrombin, to release a fluorescent molecule AMC (7-amino-4-methylcoumarin), which can be used to monitor thrombin activity. Boc-Val-Arg-AMC can be used to detect thrombin activity in plasma samples[1].

[1] Gravemann U, et al. Thrombin generation capacity of methylene blue-treated plasma prepared by the Theraflex MB plasma system[J]. Transfusion Medicine and Hemotherapy, 2009, 36(2): 122-127. DOI:10.1159/000202413