113-07-5

Anaesthetics

Doxapram Hydrochloride is a respiratory stimulant that has an inhibitory effect on myocardial IK1 potassium channel.

ChEBI: The hydrochloride salt of doxapram. A central and respiratory stimulant with a brief duration of action, both doxapram hydrochloride and its hydrate are used as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic o structive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.