ChemicalBook CAS DataBase List 1092061-61-4

1092061-61-4

Name	Crebinostat
CAS	1092061-61-4
Molecular Formula	C20H23N3O3
MDL Number	MFCD34184472
Molecular Weight	353.41
MOL File	1092061-61-4.mol

Chemical Properties

density	1.16±0.1 g/cm3(Predicted)
form	Solid
pka	9.47±0.20(Predicted)
color	White to off-white

Safety Data

Symbol(GHS)	GHS02,GHS07
Signal word	Danger
Hazard statements	H228-H315-H319
Precautionary statements	P240-P210-P241-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313

Hazard Information

Spectrum Detail

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Animal Model:	Male C57BL/6J mice (9-10 weeks)^[1]
Dosage:	25 mg/kg
Administration:	IP; alternate daily between left and right sides of the abdomen, for 10 days
Result:	Enhanced memory of contextual fear conditioning in mice; induced a trend towards an increase in total hippocampal acetylation of both H4K12 and H3K9.

1092061-61-4

Chemical Properties

Safety Data

Hazard Information

Uses

Definition

in vivo

IC 50

Spectrum Detail

Supplier

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