ChemicalBook CAS DataBase List 10378-23-1

10378-23-1

Name	Ethylenediaminetetraacetic acid tetrasodium salt dihydrate
CAS	10378-23-1
EINECS(EC#)	208-924-8
Molecular Formula	C10H16N2Na4O10
MDL Number	MFCD00007499
Molecular Weight	416.2
MOL File	10378-23-1.mol

Synonyms

2,4-DIHYDROXYAZOBENZENE-4'-SULFONIC ACID SODIUM SALT 4-(2,4-DIHYDROXYPHENYLAZO)BENZENESULFONIC ACID, SODIUM SALT ACID ORANGE 6 ACID YELLOW1 BENZENESULFONIC ACID AZORESORCINOL CHRYSOINE CHRYSOINE EX CI 14270 CI NO 14270 ECHT GELB FAST YELLOW P-(2,4-DIHYDROXYPHENYL)AZOBENZ ENESULFONIC ACID, SODIUM SALT RESORCINOL YELLOW RESORCIN YELLOW S NO 186 SODIUM 2,4-DIHYDROXYAZOBENZENE-4'-SULFONATE SODIUM 2,4-DIHYDROXYAZOBENZENE-4-SULFONATE SULFO ORANGE SULFO ORANGE IND TROPAEOLIN O

Chemical Properties

Appearance	white crystals or powder
Melting point	>300°C
Fp	350°C
storage temp.	Store at RT.
solubility	H₂O: clear, colorless
form	Liquid
color	Yellow-Orange
PH	10.5-11.5 (50g/l, H2O, 20℃)
Water Solubility	almost transparency
BRN	3861753
InChI	InChI=1S/C10H16N2O8.Na.H2O.H/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;1H2;
InChIKey	LHCZUGDUAQREMU-UHFFFAOYSA-N
SMILES	N(CC(=O)O)(CC(=O)O)CCN(CC(=O)O)CC(=O)O.[NaH].O
CAS DataBase Reference	10378-23-1(CAS DataBase Reference)

Safety Data

Symbol(GHS)	GHS05,GHS07,GHS08
Signal word	Danger
Hazard statements	H302+H332-H318-H373
Precautionary statements	P260-P280-P301+P312-P304+P340+P312-P305+P351+P338-P314
Hazard Codes	Xi
Risk Statements	R36/37/38:Irritating to eyes, respiratory system and skin . less more
Safety Statements	S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37:Wear suitable protective clothing and gloves . less more
WGK Germany	3
RTECS	DB6145180
TSCA	Yes
HS Code	29224999

Raw materials And Preparation Products

Hazard Information

Chemical Properties

white crystals or powder

Uses

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate has been used:

as a chelating agent to isolate human endometrial stem cell/stromal cells (hEnSCs) from menstrual blood
as a chelator in animal and testicular cell isolation
as a chelator for the culture of neural stem cells

Uses

Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.

General Description

Ethylenediaminetetraacetic acid (EDTA) is a chelator of metal ions. It is a substituted diamine, which has antibacterial activity. EDTA removes the undesirable effects of ferric, cupric and manganic ions in bleaching. It prevents cellular division, chlorophyll synthesis and algal biomass production. EDTA is an inhibitor of metalloprotease. It has anticoagulant property.

reaction suitability

reagent type: chelator

Biological Activity

Ethylenediaminetetraacetic acid (EDTA) is used to eliminate enzyme inhibition by traces of heavy metalsand to inhibit enzymes th at require divalent cations as cofactors.''Ethylenediaminetetraacetic acid (EDTA) is used to tre at patients poisoned with heavy metal ions. It functions as a chelator of the zinc ion in the active site of metalloproteases. EDTA inhibits other metal ion-dependent proteases such as calcium-dependent cysteine proteases. It might interfere with biological events which are metal ion-dependent. EDTA inhibits platelet aggregation and is the most preferred anticoagulant for platelet counts. It associates with other active agents to modulate microorganisms and biofilmslike citric acidalcoholantibioticspolyhexamethylene biguanide (PHMB) quaternary ammonium compoundsand other antiseptics. EDTA is used as an anticoagulant for hematological testingas it preserves the cellular components and morphology of blood cells.

Spectrum Detail

Well-known Reagent Company Product Information

Supplier

Beijing Solarbio Science & Tecnology Co., Ltd.

Telephone010-50973130 17801761073

Websitehttps://www.solarbio.com/

J & K SCIENTIFIC LTD.

Telephone18210857532 18210857532

Websitehttps://www.jkchemical.com

Meryer (Shanghai) Chemical Technology Co., Ltd.

Telephone4006356688 18621169109

Websitehttp://www.x-labseek.com/

3B Pharmachem (Wuhan) International Co.,Ltd.

Telephone 18930552037

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList13285/0_EN.htm

TCI (Shanghai) Development Co., Ltd.

Telephone021-67121386

Websitehttps://www.tcichemicals.com/CN/zh/

BeiJing Hwrk Chemicals Limted

Telephone0757-86329057 18934348241

Websitehttp://www.hwrkchemical.com/

Shandong Xiya Chemical Co., Ltd

Telephone13355009207 13355009207

Websitehttp://www.xiyashiji.com

Sichuan Kulinan Technology Co., Ltd

Telephone400-1166-196 18981987031

Websitehttp://www.hx-r.com/

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Telephone0731-85526065 13308475853

Websitehttp://www.hnhbsj.com/

Maya High Purity Chemicals

Telephone+86 (573) 82222445 (0)18006601000 452520369

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm

Spectrum Chemical Manufacturing Corp.

Telephone021-021-021-67601398-809-809-809 15221380277

Websitehttps://www.spectrumchemical.com/OA_HTML/index.jsp?minisite=10020&respid=22372&language=US

Wuhan Fortuna Chemical Co., Ltd

Telephone027-59207852 13308628970

Websitehttp://www.fortunachem.cn

Chengdu Ai Keda Chemical Technology Co., Ltd.

Telephone4008-755-333 18080918076

Websitehttp://www.aikeshiji.com

Shanghai civi chemical technology co.,Ltd

Telephone86-21-34053660

Websitehttp://www.labgogo.com

Thermo Fisher Scientific

Telephone800-810-5118

Websitehttp://www.thermo.com.cn

Shanghai T&W Pharmaceutical Co., Ltd.

Telephone+86 21 61551611

Websitehttp://www.trustwe.com

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Telephone025-66113011 13913916777

Websitehttp://www.aikonchem.com/

9ding chemical ( Shanghai) Limited

Telephone4009209199

Websitehttp://www.9dingchem.com

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