1021238-13-0

MAO-B-IN-16 is a selective monoamine oxidase B (MAO-B) inhibitor, with an IC50 of 1.55 μM. MAO-B-IN-16 can be used in the study of central nervous disorders, such as parkinson's disease[1].

hMAO-B: 1.55 μM (IC₅₀); hMAO-A: ＞100 μM (IC₅₀)

[1] Yamada M, et al. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. ACS Medicinal Chemistry Letters, 2022.