ChemicalBook CAS DataBase List 10159-53-2

10159-53-2

Name	phosphoramide mustard
CAS	10159-53-2
Molecular Formula	C4H11Cl2N2O2P
Molecular Weight	221.02
MOL File	10159-53-2.mol

Chemical Properties

Melting point	115 °C
Boiling point	363.5±52.0 °C(Predicted)
density	1.474±0.06 g/cm3(Predicted)
pka	0.41±0.50(Predicted)

Safety Data

Toxicity

LD50 intraperitoneal in mouse: 184mg/kg

Hazard Information

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Cell Line:	SIGCs
Concentration:	0.5 μM, 1 μM, 3 μM, 6 μM
Incubation Time:	48 hours
Result:	Reduced ce ll viability at concentrations of 3 μM and higher.

Cell Line:	SIGCs
Concentration:	3 μM, 6 μM
Incubation Time:	24 hours, 48 hours
Result:	Increased DDR gene mRNA expression levels.

Cell Line:	SIGCs
Concentration:	3 μM, 6 μM
Incubation Time:	24 hours, 48 hours
Result:	Generally increased DDR pro teins.

10159-53-2

Chemical Properties

Safety Data

Hazard Information

Definition

Biological Activity

in vitro

target

Supplier

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