101238-54-4

Name	Levoemopamil Hydrochloride
CAS	101238-54-4
Molecular Formula	C23H31ClN2
Molecular Weight	370.97
MOL File	101238-54-4.mol

Synonyms

Levemopamil HCl Levemopamil hydrochloride (-)-emopamilhydrochloride (S)-emopamilhydrochloride Levoemopamil Hydrochloride (-)-(S)-emopamilhydrochloride (-)-(S)-2-Isopropyl-5-(methylphenethylamino)-2-phenylvaleronitrilehydrochloride

show less show more

Hazard Information

Uses

Levemopamil hydrochloride is a blood-brain barrier penetrable calcium channel blocker and a 5-HT2 antagonist. Levemopamil hydrochloride can be used for temporary occlusion and neurological disease research[1].

in vivo

Levemopamil hydrochloride (30 mg/kg; i.p., once) regulates bilateral damping of carotid arteries (BCCA) process and reduces spatial memory deficits induced by cerebral oligemia of rats^[1].

Animal Model:	Male Han-Wistar rats with bilateral damping of carotid arteries (BCCA)^[1]
Dosage:	30 mg/kg
Administration:	Intraperitoneal injection; 30 mg/kg, once
Result:	Showed no effect on GABA or ACh content in either BCCA or sham-operated control rats. Significantly increased swimming speed of BCCA rats in swimming test. Prevented the increasing of escape latency to reach the hidden platform.

References

[1] Heim C, et al. Levemopamil injection after cerebral oligemia reduces spatial memory deficits in rats. Pharmacol Biochem Behav. 1994 Jul;48(3):613-9. DOI:10.1016/0091-3057(94)90322-0

Supplier

Shanghai EFE Biological Technology Co., Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Related Products

55837-20-2 3681-99-0

298-46-4 60142-96-3

524-95-8 67526-95-8

PROMPT×

PROMPT
The What'sApp is temporarily not supported in mainland China

Cancel

Determine

Send Inquriy