1000578-26-6

A potent 5-HT7 receptor agonist

Reported potent 5-HT 7 receptor agonist (IC 50 = 0.83 nM). In vivo, enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia.

Human 5-HT₇ Receptor: 0.83 nM (IC₅₀); Human 5-HT₇ Receptor: 0.6 nM (Ki); 5-HT_1A Receptor: 89.7 nM (Ki); 5-HT_1B Receptor: 490 nM (Ki); 5-HT_1D Receptor: 6.6 nM (Ki); 5-HT₅ Receptor: 98.5 nM (Ki)

Desiccate at -20°C

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