2-Methylpropylisocyanid

Bezeichnung:2-Methylpropylisocyanid

CAS-Nr7188-38-7

Englisch Name:TERT-BUTYL ISOCYANIDE

CBNumberCB8121846

SummenformelC5H9N

Molgewicht83.13

MOL-Datei7188-38-7.mol

Synonyma

2-Methylpropylisocyanid

2-Methylpropylisocyanid physikalisch-chemischer Eigenschaften

Schmelzpunkt	148-150 °C
Siedepunkt	91 °C(lit.)
Dichte	0.735 g/mL at 25 °C(lit.)
Brechungsindex	n20/D 1.376(lit.)
Flammpunkt	-2 °C
storage temp.	Inert atmosphere,2-8°C
Löslichkeit	Soluble in organic solvents such as ethanol, methanol, ether, toluene and dichloromethane.
Aggregatzustand	liquid
Farbe	colorless
Wichte	0.735
BRN	1903156
Expositionsgrenzwerte	NIOSH: IDLH 25 mg/m3
Stabilität	store cold
CAS Datenbank	7188-38-7(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	F,T
R-Sätze:	11-23-2017/11/23
S-Sätze:	16-45
RIDADR	UN 1993 3/PG 2
WGK Germany	3
RTECS-Nr.	EQ7102500
HazardClass	3
PackingGroup	II
HS Code	29299090

Gefahreninformationscode (GHS)

TERT-BUTYL ISOCYANIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R11:Leichtentzündlich.
R23:Giftig beim Einatmen.
S-Sätze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
clear colorless liquid
Verwenden
tert-Butyl isocyanide is used in a tin-free procedure for alkyl radical reactions in the presence of a free-radical initiator. It is a useful intermediate in multicomponent reactions. It is also used in the synthesis of coumarines, 4H-chromenes, isoxazolines and to trap 2-cyclopropylidene-1,3-diones.
synthetische
CAUTION: Use a well-ventilated hood and observe all precautions when using hydrogen cyanide.
To a 1-1, stainless steel Hoke pressure cylinder in a well-ventilated hood is added 196 gm (3.5 moles) of isobutene, 95 gm (3.5 moles) of hydrogen cyanide, and 100 gm (0.7 mole) or cuprous bromide. The cylinder is closed, shaken for 15 hr at 70°C, cooled to room temperature, and vented cautiously in the hood, and the viscous residue is poured slowly into aqueous potassium cyanide (260 gm in 100 ml of water) to decompose the cuprous complex, liberating an organic layer. The organic layer is separated, dried, and distilled under reduced pressure to afford 97 gm, b.p. 60-63°C (314 mm Hg), ng 1.3749, IR 2143 s, 1472 m, 1368 m, 1230 m, 1208 m, 855 w c m - 1; yield, 33% based on starting isobutylene; 16% based on CuBr.
synthetische
Phosgene (1.0 kg, 10.1 mol) was delivered through a wide tube into a stirred solution of N-t-butylformamide (1.01 kg, 10.0 mol) in triethylamine (1.30 kg) and o-dichlorobenzene (7.0 L) in a flask fitted with a reflux condenser charged with a freezing mixture of ice and salt (-20 C°). Water was added, the layers were separated, and the non-aqueous layer was dried over anhydrous potassium carbonate or magnesium sulfate and fractionated; bp 90–92 C°/750 mmHg; yield: 681 g (82%).
Allgemeine Beschreibung
Carbon dative bond formation by tert-butyl isocyanide on the germanium (100) surface has been reported. It also forms complexes with metals and inserts into metal-carbon bonds to form iminoacyls.

TERT-BUTYL ISOCYANIDE Upstream-Materialien And Downstream Produkte

2-Methylpropylisocyanid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

7188-38-7, TERT-BUTYL ISOCYANIDE Verwandte Suche:

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