1-Aminocyclopropanecarboxylic acid

Bezeichnung:1-Aminocyclopropanecarboxylic acid

CAS-Nr22059-21-8

Englisch Name:1-Aminocyclopropanecarboxylic acid

CBNumberCB6401146

SummenformelC4H7NO2

Molgewicht101.1

MOL-Datei22059-21-8.mol

1-Aminocyclopropanecarboxylic acid physikalisch-chemischer Eigenschaften

Schmelzpunkt	229-231 °C (lit.)
Siedepunkt	189.47°C (rough estimate)
Dichte	1.2245 (rough estimate)
Brechungsindex	1.4340 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit	DMSO (Slightly), Water (Slightly)
pka	2.29±0.20(Predicted)
Aggregatzustand	Powder and Granules
Farbe	White to off-white
Wasserlöslichkeit	Soluble in water.
BRN	2076413
Stabilität	Store in freezer at -20°C
InChI	InChI=1S/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)
InChIKey	PAJPWUMXBYXFCZ-UHFFFAOYSA-N
SMILES	C1(N)(C(O)=O)CC1
CAS Datenbank	22059-21-8(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36-37/39
WGK Germany	3
RTECS-Nr.	GZ1110000
Hazard Note	Irritant
HS Code	29213000

Gefahreninformationscode (GHS)

1-Aminocyclopropanecarboxylic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC₅₀ = 0.7-0.9 μM) in the presence of low levels (1 μM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC₅₀ = 81.6 nM) with high levels (10 μM) of glutamate. This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.
Chemische Eigenschaften
Crystalline
Verwenden
1-Aminocyclopropane-1-carboxylic Acid is a plant growth regulator. It is an NMDA agonist acting at the glycine site.
Verwenden
1-Aminocyclopropane-1-carboxylic Acid is an intermediate in the conversion of methionine to ethylene during the ripening in apples. It also plays an important role in the biosynthesis of the plant hormone ethylene.1-Aminocyclopropane-1-carboxylic Acid is shown to block convulsions and death produced by NMDA exposure, significantly reducing seizure induction and cell death of NMDA-treated hippocampal neurons. 1-Aminocyclopropane-1-carboxylic Acid is produced endogenously in the tomato and other higher plants as a product of the action of 1-aminocyclopropane-1-carboxylic acid synthase in the biosynthesis of ethylene.
Definition
ChEBI: A non-proteinogenic alpha-amino acid consisting of cyclopropane having amino and carboxy substituents both at the 1-position.
Synthesis Reference(s)
Synthetic Communications, 18, p. 141, 1988 DOI: 10.1080/00397918808077338
Synthesis, p. 127, 1984
Allgemeine Beschreibung
1-Aminocyclopropanecarboxylic acid is a member of 1-aminocycloalkanecarboxylic acids.
Biochem/physiol Actions
1-Aminocyclopropanecarboxylic acid (ACC) exhibits anticonvulsant, anxiolytic, anti-addictive, neuroprotective and antidepressant-like effects in rats and mice. ACC does not affect memory or learning processes.

1-Aminocyclopropanecarboxylic acid Upstream-Materialien And Downstream Produkte

1-Aminocyclopropanecarboxylic acid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

22059-21-8, 1-Aminocyclopropanecarboxylic acid Verwandte Suche:

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