1,5-Diphenyl-3-thiocarbazon

Bezeichnung:1,5-Diphenyl-3-thiocarbazon

CAS-Nr60-10-6

Englisch Name:Dithizone

CBNumberCB5753569

SummenformelC13H12N4S

Molgewicht256.33

MOL-Datei60-10-6.mol

Synonyma

1,5-Diphenyl-3-thiocarbazon

1,5-Diphenyl-3-thiocarbazon physikalisch-chemischer Eigenschaften

Schmelzpunkt	168 °C (dec.) (lit.)
Siedepunkt	376.1±25.0 °C(Predicted)
Dichte	1.2578 (rough estimate)
Brechungsindex	1.5700 (estimate)
storage temp.	no restrictions.
Löslichkeit	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	pK1:4.50;pK2:15 (25°C)
Aggregatzustand	Crystalline
Farbe	Black powder
Wasserlöslichkeit	Soluble in ethanol, chloroform, dimethylsulfoxide, and pyridine. Insoluble in water.
Merck	14,3377
BRN	748838
Stabilität	Stable. Incompatible with strong oxidizing agents.
CAS Datenbank	60-10-6(CAS DataBase Reference)
EPA chemische Informationen	Diazenecarbothioic acid, phenyl-, 2-phenylhydrazide (60-10-6)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	22-36/37/38
S-Sätze:	36-26
RIDADR	2811
WGK Germany	3
RTECS-Nr.	LQ9450000
TSCA	Yes
HazardClass	6.1
PackingGroup	III
HS Code	29309090

Gefahreninformationscode (GHS)

Dithizone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
dark brown or black crystals
Verwenden
Dithizone is used as an indicator for minute amounts of lead. It acts as a chelating agent for heavy metal poisoning. As a ligand, it forms complexes with metals like zinc, lead and mercury. Further, it is used to assess the purity of human pancreatic islet preparations, which is used for transplantation in patients with type 1 diabetes. In addition to this, it is used as a titrant in the quantitative determination of heavy metals.
Verwenden
Dithizone is an organosulfur compound that acts as a chelating agent and forms complexes with metals such as lead and mercury. Dithizone is used to assess the purity of human pancreatic islet preparations used for transplantation into patients with type 1 diabetes.
Verwenden
Sensitive reagent for several heavy metals, Co, Cu, Pb, and Hg; especially for the estimation of minute amounts of Pb.
Definition
ChEBI: Dithizone is a member of phenylhydrazines.
Allgemeine Beschreibung
Dithizone (Diphenylthiocarbazone) is used as chelating agent for zinc. It is widely used for the liquid-liquid and solid phase extraction of various metals since it forms stable complexes with the metals.
läuterung methode
The crude dithizone is dissolved in CCl4 to give a concentrated solution. This is filtered through a sintered glass funnel and shaken with 0.8M aqueous ammonia to extract dithizonate ion. The aqueous layer is washed with several portions of CCl4 to remove undesirable materials. The aqueous layer is acidified with dilute H2SO4 to precipitate pure dithizone. This is dried in a vacuum. When only small amounts of dithizone are required, purification by paper chromatography is convenient. [Cooper & Hibbits J Am Chem Soc 75 5084 1933.] Instead of CCl4, CHCl3 can be used, and the final extract, after washing with water, can be evaporated in air at 40-50o and dried in a desiccator. It complexes with Cd, Hg, Ni and Zn. [Beilstein 16 H 26, 16 IV 18.]

Dithizone Upstream-Materialien And Downstream Produkte

1,5-Diphenyl-3-thiocarbazon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

60-10-6, Dithizone Verwandte Suche:

Send Inquriy