DYCLONINE

DYCLONINE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Dyclone,Dow,US,1956

• Verwenden

  anesthetic (local)

• Definition

  ChEBI: N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group.

• Manufacturing Process

  A mixture of 17.6 grams of p-n-butoxyacetophenone, 12.1 grams of piperidine hydrochloride, 4.5 grams paraformaldehyde, 0.25 cc concentrated hydrochloric acid, 52.5 cc nitroethane, 7.5 cc of 95% ethanol, and 15 cc of toluene was boiled under reflux for one hour, removing water formed in the reaction by means of a condensate trap. The mixture was then cooled. The crystals which formed were collected by filtration, washed with anhydrous ether and recrystallized from methyl ethyl ketone. The crystals thus obtained, which melted at 174-175°C, were shown by analysis to be 4-n-butoxy-β- piperidinopropiophenone hydrochloride.

• Trademarks

  Dyclone (AstraZeneca).

• Therapeutic Function

  Local anesthetic

DYCLONINE Upstream-Materialien And Downstream Produkte

DYCLONINE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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