Salicylsäure-ethylester

Bezeichnung:Salicylsäure-ethylester

CAS-Nr118-61-6

Englisch Name:Ethyl 2-hydroxybenzoate

CBNumberCB1723193

SummenformelC9H10O3

Molgewicht166.17

MOL-Datei118-61-6.mol

Synonyma

Ethylsalicylat

Salicylsäure-ethylester

Salicylsäure-ethylester physikalisch-chemischer Eigenschaften

Schmelzpunkt	1 °C (lit.)
Siedepunkt	234 °C (lit.)
Dichte	1.131 g/mL at 25 °C (lit.)
Dampfdruck	0.05 mm Hg ( 25 °C)
Brechungsindex	n20/D 1.522(lit.)
FEMA	2458 \| ETHYL SALICYLATE
Flammpunkt	225 °F
storage temp.	Store below +30°C.
Löslichkeit	0.25g/l
Aggregatzustand	Liquid
pka	9.93±0.10(Predicted)
Farbe	Clear colorless to pale yellow
Geruch (Odor)	at 100.00 %. sweet wintergreen mint floral spicy balsam
Geruchsart	minty
Explosionsgrenze	1.1%(V)
Wasserlöslichkeit	slightly soluble
Merck	14,3850
JECFA Number	900
BRN	907659
Dielectric constant	8.6（21℃）
InChIKey	GYCKQBWUSACYIF-UHFFFAOYSA-N
LogP	3.07 at 21.9℃
CAS Datenbank	118-61-6(CAS DataBase Reference)
NIST chemische Informationen	Benzoic acid, 2-hydroxy-, ethyl ester(118-61-6)
EPA chemische Informationen	Ethyl salicylate (118-61-6)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	22-36/38-52/53
S-Sätze:	26-36
WGK Germany	1
RTECS-Nr.	VO3000000
TSCA	Yes
HS Code	29182390
Toxizität	LD50 orally in Rabbit: 1320 mg/kg LD50 dermal Rabbit > 5000 mg/kg

Gefahreninformationscode (GHS)

Ethyl 2-hydroxybenzoate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/38:Reizt die Augen und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Ethyl 2-hydroxdybenzoate is also known as Ethyl salicylate, which a kind of ester formed through the condensation between salicylic acid and ethanol. It can be used as a perfumery, artificial essence flavoring agent and used in cosmetics. It can also be used as analgesics, anti-inflammatory and antipyretic agents.
Chemische Eigenschaften
clear colourless to pale yellow liquid
Chemische Eigenschaften
Ethyl salicylate has a characteristic aromatic odor similar to wintergreen. It tends to darken on exposure to light and air.
Chemische Eigenschaften
Ethyl salicylate is the ester formed by the condensation of salicylic acid and ethanol. It is a clear liquid that is sparingly soluble in water, but soluble in alcohol and ether. It has a pleasant odor resembling winter green and is used in perfumery and artificial flavors.
Occurrence
Reported found in raspberry, tomato, currants, rum, whiskey, red wine, plum brandy, Cape gooseberry, Feijoa fruit, papaya and scotch.
Verwenden
manufacture of artificial perfumes.
Verwenden
Ethyl salicylate may be used as an analytical standard for the determination of the analyte in biological fluids and topical formulation by chromatography-based techniques.
Verwenden
Ethyl salicylate is a non-steroidal analgesic, anti-inflammatory and antirrheumatic drug. Its complexation with β-cyclodextrin was studied using reversed-phase liquid chromatography.
Definition
ChEBI: Ethyl salicylate is a hydroxybenzoic acid.
Vorbereitung Methode
Ethyl salicylate is found naturally in currants and strawberries . It is manufactured commercially by the esterification of salicylic acid with ethyl alcohol.
synthetische
By esterification of salicylic acid with ethyl alcohol and concentrated H2SO4 at 100°C in the presence of aluminum sulfate; by heating to the boil an alkaline solution of salicylic acid and ethyl p-toluenesulfonate.
Taste threshold values
Taste characteristics at 10 ppm: sweet, wintergreen, spicy and anisic.
Allgemeine Beschreibung
Ethyl salicylate was hydrolysed to salicylic acid by the use of an extractive electrospray ionisation (EESI) device.
Flammability and Explosibility
Not classified
Einzelnachweise
Sheu, Yaw-Wen, and Chein-Hsiun Tu. "Densities and viscosities of binary mixtures of ethyl acetoacetate, ethyl isovalerate, methyl benzoate, benzyl acetate, ethyl salicylate, and benzyl propionate with ethanol at T=(288.15, 298.15, 308.15, and 318.15) K." Journal of Chemical & Engineering Data 51.2 (2006): 545-553.
Filippa, Mauricio, Matías I. Sancho, and Estela Gasull. "Encapsulation of methyl and ethyl salicylates by β-cyclodextrin: HPLC, UV–vis and molecular modeling studies." Journal of pharmaceutical and biomedical analysis 48.3 (2008): 969-973.

Ethyl 2-hydroxybenzoate Upstream-Materialien And Downstream Produkte

Salicylsäure-ethylester Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

118-61-6, Ethyl 2-hydroxybenzoate Verwandte Suche:

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