5-Methylresorcin

Bezeichnung:5-Methylresorcin

CAS-Nr504-15-4

Englisch Name:Orcinol

CBNumberCB1682973

SummenformelC7H8O2

Molgewicht124.14

MOL-Datei504-15-4.mol

Synonyma

5-Methylresorcin

5-Methylresorcin physikalisch-chemischer Eigenschaften

Schmelzpunkt	106-112 °C(lit.)
Siedepunkt	290 °C
Dichte	1.2900
Brechungsindex	1.4922 (estimate)
Flammpunkt	159 °C
storage temp.	Store at <= 20°C.
Löslichkeit	80g/l
Aggregatzustand	Crystalline Powder or Crystals
pka	9.56±0.10(Predicted)
Farbe	Pink-gray to pink-brown
Sensitive	Air Sensitive
Merck	14,6864
BRN	1071903
Stabilität	Hygroscopic
InChIKey	OIPPWFOQEKKFEE-UHFFFAOYSA-N
LogP	1.221 (est)
CAS Datenbank	504-15-4(CAS DataBase Reference)
NIST chemische Informationen	3,5-Dihydroxytoluene(504-15-4)
EPA chemische Informationen	1,3-Benzenediol, 5-methyl- (504-15-4)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22-36/37/38-41-37/38-20/21/22
S-Sätze:	22-26-36-37/39
RIDADR	2811
WGK Germany	3
RTECS-Nr.	VH2100000
TSCA	Yes
PackingGroup	III
HS Code	29072900
Toxizität	LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 5000 mg/kg

Gefahreninformationscode (GHS)

Orcinol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R41:Gefahr ernster Augenschäden.
R37/38:Reizt die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
pink-grey to pink-brown powder or crystals.
Verwenden
Orcinol can be used to synthesize:
Orcinol-containing azacryptands for use in optical amplifiers and light-emitting devices.
Ternary co-crystal with 4,4′-bipyridine.
Low-density carbon aerogels in the presence of formaldehyde.
PEG-orcinol coumarins with potent tyrosinase inhibitory activity.
Application
Orcinol is found in many lichen species and It is used as an analytical reagent for pentoses, lignin, beet sugar, saccharoses, arabinose, and diastase. The orcinol assay was used for the direct assay of the number of glycolipids presents in the sample. The orcinol reagent was prepared by adding concentrated sulphuric acid, H2SO4 (98% w/w) and 0.19% orcinol (3,5-dihydroxytoluene) to distilled water.
Definition
ChEBI: Orcinol is a 5-alkylresorcinol in which the alkyl group is specified as methyl. It has a role as an Aspergillus metabolite. It is a 5-alkylresorcinol and a dihydroxytoluene.
synthetische
Orcinol has been isolated from numerous lichen fungi (Robiquet, 1829) and can be synthesized by decarboxylation of orsellinic acid in Umbilicaria papulosa and Gliocladium roseum (Pettersson, 1965; Mosbach and Ehrensvard, 1966).
Orcinol was first prepared by dehydroacetic acid, a conversion that involved ring-opening of the pyrone to a triketone. This early experiment helped establish the rich condensation chemistry of polyketides. It can be obtained by fusing extract of aloes with potash, followed by acidification.
US3865884A: Preparation of orcinol
Biologische Aktivität
Orcinol is a compound obtained from DHA which can mimic the biogenetic synthesis of phenolic compounds.
Orcinol is a polyketide synthase-derived phenol that has been found in F. graminearum and has diverse biological activities. It scavenges DPPH radicals (IC50 = 2.93 mM). Orcinol (2.5 and 5 mg/kg) increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity. It has also been used in the colorimetric detection of carbohydrates.
Sicherheitsprofil
Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion and intraperitoneal routes. Mildly toxic by skin contact. When heated to decomposition it emits acrid smoke and irritating fumes.
target
ERK | BDNF
läuterung methode
Crystallise orcinol from CHCl3/*benzene (2:3). See hydrate in previous entry. [Beilstein 6 H 882, 6 IV 5892.]

Orcinol Upstream-Materialien And Downstream Produkte

5-Methylresorcin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

504-15-4, Orcinol Verwandte Suche:

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