2-Cyan-3-(4-hydroxyphenyl)acrylsure

Bezeichnung:2-Cyan-3-(4-hydroxyphenyl)acrylsure

CAS-Nr28166-41-8

Englisch Name:ALPHA-CYANO-4-HYDROXYCINNAMIC ACID

CBNumberCB0781327

SummenformelC10H7NO3

Molgewicht189.17

MOL-Datei28166-41-8.mol

Synonyma

2-Cyan-3-(4-hydroxyphenyl)acrylsure

2-Cyan-3-(4-hydroxyphenyl)acrylsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	245-250 °C(lit.)
Siedepunkt	324.41°C (rough estimate)
Dichte	1.3175 (rough estimate)
Brechungsindex	1.5400 (estimate)
storage temp.	2-8°C
Löslichkeit	methanol: 10 mg/mL, clear
Aggregatzustand	powder
pka	0.85±0.10(Predicted)
Farbe	yellow
BRN	3271427
InChIKey	AFVLVVWMAFSXCK-VMPITWQZSA-N
CAS Datenbank	28166-41-8(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	3
F	10-23
HS Code	29269090

Gefahreninformationscode (GHS)

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
yellow crystalline powder
Verwenden
α-Cyano-4-hydroxycinnamic acid(CHC) was used as a matrix for peptides and nucleotides in mass spectroscopic analysis. It was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.
Verwenden
α-Cyano-4-hydroxycinnamic acid (CHC) was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.
Verwenden
inhibitor of mitochondrial pyruvate transport
Definition
ChEBI: Alpha-cyano-4-hydroxycinnamic acid is a monohydroxycinnamic acid that is 4-hydroxycinnamic acid in which the hydrogen alpha- to the carboxy group is replaced by a cyano group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of peptides and oligonucleotides. It has a role as a MALDI matrix material. It is a nitrile, a member of phenols and a monohydroxycinnamic acid.
Allgemeine Beschreibung
α-Cyano-4-hydroxycinnamic acid is the commonly used matrix for analyzing peptides by matrix-assisted laser desorption/ionization mass spectrometry. It inhibits the monophenolase activity and diphenolase activity of mushroom tyrosinase.
Biochem/physiol Actions
α-Cyano-4-hydroxycinnamic acid acts as a specific inhibitor of monocarboxylic acid transport, including lactate and pyruvate transport. It is also reported to block β-cell apical anion exchange (IC50 of 2.4 mM).
Lager
Store at +4°C

2-Cyan-3-(4-hydroxyphenyl)acrylsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

28166-41-8, ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Verwandte Suche:

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