Benzo[b]thiophen

Bezeichnung:Benzo[b]thiophen

CAS-Nr95-15-8

Englisch Name:Thianaphthene

CBNumberCB0683988

SummenformelC8H6S

Molgewicht134.2

MOL-Datei95-15-8.mol

Synonyma

Benzo[b]thiophen

Benzo[b]thiophen physikalisch-chemischer Eigenschaften

Schmelzpunkt	30-33 °C
Siedepunkt	221-222 °C(lit.)
Dichte	1.149 g/mL at 25 °C(lit.)
Brechungsindex	1.6332 (estimate)
Flammpunkt	>230 °F
storage temp.	Store below +30°C.
Löslichkeit	0.13g/l
Aggregatzustand	Crystalline Solid
pka	32.4
Wichte	1.149
Farbe	White to pink or yellow
Wasserlöslichkeit	insoluble
Merck	14,9303
BRN	80580
InChIKey	FCEHBMOGCRZNNI-UHFFFAOYSA-N
LogP	3.120
CAS Datenbank	95-15-8(CAS DataBase Reference)
NIST chemische Informationen	Benzo[b]thiophene(95-15-8)
EPA chemische Informationen	Benzo[b]thiophene (95-15-8)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi,N
R-Sätze:	22-36/37/38-20/21/22-51/53
S-Sätze:	22-24/25-36-26-61
RIDADR	UN3077
WGK Germany	3
Hazard Note	Irritant
TSCA	Yes
HazardClass	9
PackingGroup	III
HS Code	29349990

Gefahreninformationscode (GHS)

Thianaphthene Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
WHITE TO RED CRYSTALLINE LOW MELTING SOLID
Verwenden
Benzo[b]thiophene is used in the preparation of 2-thianapthenylphenyllithium, via metalation by n-butyllithium. It is used in organic as well as pharmaceutical industry as a component in the synthesis of raloxifene, a breast cancer therapeutic, or hydrodesulfurization reactions.
Verwenden
Benzo[b]thiophene has application in organic as well as pharmaceutical industry as a component in the synthesis of Raloxifene, a breast cancer therapeutic, or hydrodesulfurization reactions.
Verwenden
Thianaphthene may be used in the preparation of 2-thianapthenylphenyllithium, via metalation by n-butyllithium.
Verwenden
manufacture of pharmaceuticals, thioindigo.
Definition
ChEBI: 1-benzothiophene is a benzothiophene and a member of 1-benzothiophenes.
Application
Thianaphthene may be used in the preparation of 2-thianapthenylphenyllithium, via metalation by n-butyllithium.
Reaction of ethyl diazoacetate with thianaphthene has been reported.
Synthesis Reference(s)
Journal of the American Chemical Society, 69, p. 2008, 1947 DOI: 10.1021/ja01200a053
Tetrahedron, 27, p. 1253, 1971 DOI: 10.1016/S0040-4020(01)90874-9
Allgemeine Beschreibung
Reaction of ethyl diazoacetate with thianaphthene has been reported.
läuterung methode
1-Benzothiophene has the odour of naphthalene. If the IR spectrum is not very good, then suspend it in a faintly alkaline aqueous solution and steam distil it. Extract the distillate with Et2O, dry the extract (CaCl2), filter, evaporate the solvent and fractionate the residue. The distillate sets solid. The sulfoxide has m 142o, the picrate has m 148-149o (yellow crystals from EtOH) and the styphnate has m 136-137o. [Hansch & Lindwall J Org Chem 10, 381 1945, Meyer & Meyer Chem Ber 52B 1249 1919, Weisgerber & Kruber 53 1551 1920, Iddon & Scrowston Adv Heterocycl Chem 11 177 1970, Beilstein 17/2 V 6.]

Thianaphthene Upstream-Materialien And Downstream Produkte

Benzo[b]thiophen Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

95-15-8, Thianaphthene Verwandte Suche:

Send Inquriy