PPARγ FL (human recombinant from E. coli)

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor family of ligand activated transcription factors that heterodimerizes with retinoic acid-like receptors to regulate gene expression and differentiation.1 The PPAR family of nuclear hormone receptors consists of three subtypes encoded by separate genes: PPARα, PPARδ (also referred to as hNUC1, PPARβ, or FAAR), and PPARγ. Among them PPARγ is the most widely studied and has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis, and cancer.2 PPARγ is primarily expressed in adipose tissue and to a lesser extent in the colon, immune system, and the retina.3 PPARγ FL (human, recombinant from E. coli) purity was determined using gel electrophoresis followed by coomassie staining.WARNING This product is not for human or veterinary use.