Hormone Sensitive Lipase (human recombinant)

Hormone-sensitive lipase (HSL) is a key enzyme regulating the mobilization of fatty acids from intracellular stores.1 There are three different isoforms of the enzyme: HSLadi, which is the predominant form found in adipocytes, HSLtes expressed in testes, and HSLb found in insulin secreting β-cells.2 The three isoforms are distinguished by their molecular masses.2 HSL catalyses the rate limiting step in the lipolysis of triacylglycerol, found in intracellular stores, to fatty acids.3 HSL also catalyzes the hydrolysis of mono- and diacylglycerides, as well as cholesterol esters.4WARNING This product is not for human or veterinary use.