Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility
H2O: >4 mg/mL
pka
9.05±0.13(Predicted)
form
solid
color
yellow
Description
Norfluoxetine is an active metabolite of the antidepressant fluoxetine that inhibits serotonin uptake with a pKi value of 7.35. The S-enantiomer of norfluoxetine has 20-times higher serotonin reuptake blocking potency than the R-enantiomer (pKis = 7.86 versus 6.51, respectively).