![ChemicalBook](https://m.chemicalbook.com/Scripts/New/img/logo.png)
![структурированное изображение](/CAS/GIF/13476-25-0.gif)
LINDERANE
- русский язык имя
- английское имяLINDERANE
- CAS №13476-25-0
- CBNumberCB9243408
- ФормулаC15H16O4
- мольный вес260.29
- номер MDLMFCD07781424
- файл Mol13476-25-0.mol
химическое свойство
Температура плавления | 190~191℃ |
Температура кипения | 434.5±45.0 °C(Predicted) |
плотность | 1.30±0.1 g/cm3(Predicted) |
температура хранения | -20°C |
растворимость | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
форма | Solid |
цвет | White to Off-White |
Стабильность | Hygroscopic |
Заявления о безопасности | 24/25 |
кода HS | 29322090 |
LINDERANE химические свойства, назначение, производство
Описание
Linderane is a sesquiterpene that has been found in L. aggregata. It inhibits the cytochrome P450 (CYP) isoform CYP2C9 (Ki = 1.26 μM) in an irreversible and NADPH-dependent manner. Linderane decreases phosphoenolpyruvate carboxykinase (Pck1) and glucose-6-phosphatase (G6pc) gene expression, cAMP concentration, and CREB phosphorylation, increases phosphodiesterase 3 (PDE3) activity, and inhibits gluconeogenesis in rat primary hepatocytes. In vivo, linderane (50 mg/kg twice per day) decreases serum and hepatic triglyceride levels, as well as random-fed and fasting blood glucose levels in ob/ob mice.Использование
Linderane is a sequiterpene lactone extract from Lindera strychnifolia compound used as a cytotoxic agent against hepaic stellate cells.LINDERANE поставщик
поставщик | телефон | страна | номенклатура продукции | благоприятные условия |
---|---|---|---|---|
+86-0371-55170693 +86-19937530512 |
China | 21667 | 55 | |
18017610038 | CHINA | 3620 | 58 | |
+86-0371-86658258 +8613203830695 |
China | 29889 | 58 | |
+8618080483897 | China | 3777 | 58 | |
18871490254 | CHINA | 28180 | 58 | |
+86-023-6139-8061 +86-86-13650506873 |
China | 39916 | 58 | |
18502101150 | CHINA | 1923 | 58 | |
+86-0519-85557386 +8613815050216 |
China | 10307 | 58 | |
+86-27-8439 4403 18971486879 |
CHINA | 2935 | 58 | |
+86-0551-65418671 +8618949823763 |
China | 34571 | 58 |