acetyl carbromal

Создатель

Acetylcarbromal ,Pfaltz and Bauer

Производственный процесс

It was mixed 120 parts of urea and 258 parts of bromodiethylacetylbromide (prepared from diethylacetic acid anhydride and bromine). After 12 hours the mixture was heated for 3 hours at 100°C. The product was mixed with an aqueous solution of sodium bicarbonate and then was filtered. The obtained bromodiethylacetylurea was crystallized from diluted ethanol; melting point 114-118°C. The mixture of 474 parts of bromodiethylacetylurea, 1000 parts of acetic anhydride and 75 parts ZnCl2 was heated at 60°C for 1 hour. The product was stirred with 3000 parts of ice-water and then 1-acetyl-3-(α- bromo-α-ethylbutyryl)urea was filtered; melting point 108-109°C.

Терапевтическая функция

Sedative, Hypnotic