Дицикловерин

Использование

Anticholinergic.

Определение

ChEBI: The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularl that associated with irritable bowel syndrome.

Всемирная организация здравоохранения(ВОЗ)

Dicycloverine, an anticholinergic agent with antispasmodic and local anaesthetic activity, was introduced in 1952 for treatment of functional conditions involving smooth muscle of the gastrointestinal tract. Its use in the treatment of colic in infants under six months of age has been associated with irritability and restlessness, convulsions and apnoea which has led the major manufacturer to issue revised global prescribing information in 1985 contraindicating the use of dicycloverine in this age group. Subsequently restrictive regulatory action directed to other available brands of this drug was taken in several countries. Preparations containing dicycloverine remain available in at least ten major markets.