Диметистерон
- английское имяDIMETHISTERONE
- CAS №79-64-1
- CBNumberCB8702265
- ФормулаC23H32O2
- мольный вес340.5
- EINECS201-215-4
- номер MDLMFCD00867870
- файл Mol79-64-1.mol
химическое свойство
| Температура плавления | 102° |
| альфа | D20 +10° (c = 1 in chloroform) |
| Температура кипения | 416.28°C (rough estimate) |
| плотность | 1.0555 (rough estimate) |
| показатель преломления | 1.4480 (estimate) |
| пка | 13.03±0.70(Predicted) |
| FDA UNII | OIC9M646C5 |
| Система регистрации веществ EPA | Dimethisterone (79-64-1) |
Диметистерон химические свойства, назначение, производство
Создатель
Oracon,Mead Johnson,US,1965Производственный процесс
A solution of a Grignard reagent, employing 1-propyne (8 grams) was prepared. To this reagent there was added the 3,3 ethylenedioxy derivative (4 grams) of 6-α-methylandrost-4-ene-3,17-dione in tetrahydrofuran (100 ml), and the mixture heated under reflux for 3 hours. After decomposition of the complex with aqueous ammonium chloride, the product was isolated with ether and treated with 90% acetic acid (50 ml) for 30 minutes at 100°C. The product obtained by pouring the mixture into water and extracting with ether was crystallized from aqueous methanol. 17β-Hydroxy-6α-methyl-17α-(prop- 1-ynyl)androst-4-en-3-one formed plates MP 99° to 102°C.Терапевтическая функция
ProgestinДиметистерон запасные части и сырье
Диметистерон поставщик
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