2-АМИНО-3,4-ДИМЕТИЛ-3H-ИМИДАЗО [4,5-F]ХИНОЛИН

Химические свойства

Yellow Crystalline Solid

Использование

Mutagenic heterocyclic amines in cooked food

Методы производства

Heterocyclic amines are formed by condensation of creatinine with amino acids during heating or cooking of meat (beef, pork, chicken, and fish). They have also been detected in processed food flavorings, beer, wine, and cigarette smoke. 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ) and related heterocyclic amines are produced in small quantities for research purposes. Exposure to MeIQ and related heterocyclic amines occurs primarily through the consumption of cooked meats.Concentrations of heterocyclic amines in meats varied under different cooking conditions (375). The highest concentrations of MeIQ were detected in grilled fish, which appear to be the major dietary source of heterocyclic amines in Japanese. U.S. surveys of dietary intakes of heterocyclic amines in cooked foods have also been reported. Occupational exposure to heterocyclic amines may occur by inhalation of aerosolized particles formed during the cooking process.

Общее описание

Pale orange crystalline solid or light yellow powder.

Реакции воздуха и воды

2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE is sensitive to light and air. Slightly water soluble .

Профиль реактивности

2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE is rapidly degraded by dilute hypochlorite.

Угроза здоровью

ACUTE/CHRONIC HAZARDS: 2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE may emit potentially toxic fumes when involved in a fire.

Пожароопасность

Flash point data for 2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE are not available; however, 2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE is probably combustible.

Профиль безопасности

Confirmed carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.

Канцерогенность

MeIQ is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and supporting genotoxicity data.