(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
- русский язык имя
- английское имя(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
- CAS №141388-76-3
- CBNumberCB82470922
- ФормулаC19H21ClFN3O3
- мольный вес393.84
- EINECS604-773-0
- номер MDLMFCD00917502
- файл Mol141388-76-3.mol
химическое свойство
| Температура кипения | 607.0±55.0 °C(Predicted) |
| плотность | 1.469 |
| температура хранения | Store at -20°C |
| растворимость | DMSO: Insoluble; |
| пка | 6.41±0.50(Predicted) |
| Растворимость в воде | Water: Insoluble |
| FDA UNII | BFE2NBZ7NX |
| Код УВД | S01AE08 |
(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid химические свойства, назначение, производство
Химические свойства
Yellow to slightly yellow crystalline powderФармацевтические приложения
An amino-azepinyl quinolone formulated as a suspension for ophthalmic usage. It exhibits good antistaphylococcal activity, as well as activity against Str. pneumoniae, Enterobacteriaceae, H. influenzae and Mor. catarrhalis. It is weakly active against Corynebacterium spp. and has no useful activity against Ps. aeruginosa. After instillation into the eye, less than 0.1% of the drug reaches the plasma. It is used for bacterial conjunctivitis.(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid поставщик
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