Пипациклин

английское имяpipacycline
CAS №1110-80-1
CBNumberCB7928471
ФормулаC29H38N4O9
мольный вес586.638
EINECS214-176-3
номер MDLMFCD00864861
файл Mol1110-80-1.mol

химическое свойство

альфа	D20 -195° (c = 0.5); D20 -175° (c = 0.5 in methanol)
Температура кипения	895.8±65.0 °C(Predicted)
плотность	1.55±0.1 g/cm3(Predicted)
температура хранения	Store at -20°C
растворимость	Soluble in DMSO
пка	4.50±1.00(Predicted)
FDA UNII	PQ3P6082I5

Заявления об опасности и безопасности

Токсичность

LD50 i.v. in white mice: 188 mg/kg (Scalvini, Delmonte)

Пипациклин химические свойства, назначение, производство

Использование

Pipacycline (mepicycline) is a semi-synthetic tetracycline formed by a Mannich condensation of formaldehyde and 4-hydroxyethylpiperazine with tetracycline. The introduction of the piperazine improves bioavailability, but Mannich bases are pro-drugs, converting back to the parent compound. Pipacycline is used commercially as a salt in combination with penicillin V for parenteral use (penimepicycline). The intrinsic in vitro activity and SARs for the amide region of the tetracycline molecule have not investigated extensively. Pipacycline has not been extensively cited in the literature.

Определение

ChEBI: Tetracycline in which a hydrogen attached to the amide nitrogen is substituted by a 4-[(2-hydroxyethyl)piperazin-1-yl]methyl group.

Пипациклин запасные части и сырье

сырьё

Пипациклин поставщик

поставщик	телефон	страна	номенклатура продукции	благоприятные условия
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30253	58
BOC Sciences	16314854226; +16314854226	United States	19743	58
Lynnchem	86-(0)29-85992781 17792393971	China	4587	58
Novachemistry	44-20819178-90 02081917890	United Kingdom	4381	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	China	6870	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	China	56070	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	China	11289	58
Meng Cheng Technology (Shanghai) Co., LTD	400-820-6829	China	8864	58
Hubei Xinyang Medical Technology Co., Ltd	15347293736 15347293736	China	8378	58
Energy Chemical	021-58432009 400-005-6266	China	44843	58

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