SCUTELLAREIN
- русский язык имя
- английское имяSCUTELLAREIN
- CAS №529-53-3
- CBNumberCB6402688
- ФормулаC15H10O6
- мольный вес286.24
- EINECS1806241-263-5
- номер MDLMFCD00017692
- файл Mol529-53-3.mol
химическое свойство
Температура плавления | 330°C |
Температура кипения | 642.9±55.0 °C(Predicted) |
плотность | 1.654±0.06 g/cm3(Predicted) |
температура хранения | Sealed in dry,2-8°C |
растворимость | DMSO: soluble1mg/mL, clear, greenish-yellow |
пка | 6.34±0.40(Predicted) |
форма | powder |
цвет | yellow |
ИнЧИКей | JVXZRQGOGOXCEC-UHFFFAOYSA-N |
LogP | 2.540 (est) |
FDA UNII | P460GTI853 |
Заявления о безопасности | 24/25 |
WGK Германия | 3 |
кода HS | 29329990 |
SCUTELLAREIN химические свойства, назначение, производство
Описание
Scutellarein is a flavone that has been isolated from S. baicalensis and has antioxidant, enzyme inhibitory, anti-inflammatory, and antiproliferative biological activities. It has antioxidant activity in a total reactive antioxidant potential (TRAP) assay when used at a concentration of 1 μg/ml. Scutellarein inhibits sucrose hydrolysis by rat intestinal α-glucosidase and ATPase activity of the severe acute respiratory syndrome (SARS) coronavirus helicase nsP13 (IC50s = 12 and 0.86 μM, respectively). It decreases nitric oxide (NO) release and mRNA expression of inducible NO synthase (iNOS) and TNF-α induced by LPS in RAW 264.7 macrophages when used at a concentration of 50 μM. In vivo, scutellarein (0.5 μg/g) decreases tumor weight and volume in an HT-1080 human fibrosarcoma mouse xenograft model.Химические свойства
Yellow solidИспользование
Scutellarein is a flavonoid that can be found in Scutellaria lateriflora. Scutellarein is a hydrolysis product of Scutellarein (S201900), its glucuronide conjugated analogue.Определение
ChEBI: Flavone substituted with hydroxy groups at C-4', -5, -6 and -7.SCUTELLAREIN запасные части и сырье
запасной предмет
SCUTELLAREIN поставщик
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