SUC-Leu-Leu-Val-Tyr-АМС
- английское имяSUC-LEU-LEU-VAL-TYR-AMC
- CAS №94367-21-2
- CBNumberCB6290865
- ФормулаC40H53N5O10
- мольный вес763.88
- номер MDLMFCD00080248
- файл Mol94367-21-2.mol
химическое свойство
| Температура кипения | 1116.8±65.0 °C(Predicted) |
| плотность | 1.249±0.06 g/cm3(Predicted) |
| температура хранения | -20°C |
| растворимость | Soluble in DMSO (up to 20 mg/ml), or in DMF (up to 10 mg/ml) |
| форма | Lyophilized solid |
| пка | 4.69±0.10(Predicted) |
| цвет | White to Off-White |
| Растворимость в воде | 0.1% trifluoroacetic acid in acetonitrile: water (3:1): 1mg/mL, clear, colorless |
| Последовательность | Suc-Leu-Leu-Val-Tyr-AMC |
| Стабильность | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 1 month. |
| FDA UNII | 7GVY2DYZ80 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SUC-Leu-Leu-Val-Tyr-АМС химические свойства, назначение, производство
Использование
Suc-Leu-Leu-Val-Tyr-AMC is a fluorgenic substrate for chymotrypsin-like proteases, as well as calpains. It can be used to treat tuberculosis.Определение
ChEBI: A tetrapeptide compound with a succinyl group at the N-terminal and a 7-amino-4-methylcoumarin group at the C-terminal.Биохимия/физиол Действия
In the presence of chymotrypsin-like enzyme activity, the fluorophore, 7-amido-4-methylcoumarin is released from N-succinyl-Leu-Leu-Val-Tyr-7-amido-4-methylcoumarin. The fluorescence obtained is a measure of the enzyme activity.6SUC-Leu-Leu-Val-Tyr-АМС поставщик
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