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![P1,P5-Di(adenosine-5′) pentaphosphate trilithium salt структурированное изображение](/CAS/GIF/75522-97-3.gif)
P1,P5-Di(adenosine-5′) pentaphosphate trilithium salt
- английское имяP1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT
- CAS №75522-97-3
- CBNumberCB6278012
- ФормулаC20H26Li3N10O22P5
- мольный вес934.17
- EINECS278-237-6
- номер MDLMFCD00044936
- файл Mol75522-97-3.mol
химическое свойство
температура хранения | -20°C |
растворимость | H2O: soluble50mg/mL |
форма | powder |
цвет | white to off-white |
P1,P5-Di(adenosine-5′) pentaphosphate trilithium salt химические свойства, назначение, производство
Химические свойства
White powderИспользование
P1,P5-Di(adenosine-5′) pentaphosphate trilithium salt has been used as a adenylate kinase inhibitor and as a component of pre-AMPPNP rigor solution for treating muscle fibres.Биохимия/физиол Действия
A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor.P1,P5-Di(adenosine-5′) pentaphosphate trilithium salt поставщик
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