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Пимагедин
- английское имяpimagedine
- CAS №79-17-4
- CBNumberCB5875700
- ФормулаCH6N4
- мольный вес74.09
- EINECS201-183-1
- номер MDLMFCD00242587
- файл Mol79-17-4.mol
химическое свойство
Температура плавления | 182-185 °C (decomp) |
Температура кипения | 159.5±23.0 °C(Predicted) |
плотность | 1.72±0.1 g/cm3(Predicted) |
показатель преломления | 1.6660 (estimate) |
пка | 11.08±0.70(Predicted) |
FDA UNII | SCQ4EZQ113 |
Пимагедин химические свойства, назначение, производство
Использование
Inhibitor (advanced glycosylation end-product formation).Определение
ChEBI: Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.Ферментативный ингибитор
This substituted hydrazine (FWhydrochloride = 110.55 g/mol; CAS 79-17-4), also named pimagedine, is a strong inhibitor of diamine oxidases as well as nitric oxide synthase. Note that aminoguanidine also inhibits the formation of advanced glycosylation end-products, reportedly by reacting with and trapping Amadori rearrangement-derived fragmentation products in solution. In view of this property, aminoguanidine has often been used to treat complications associated with chronic diabetes. Target(s): amine oxidase (copper-containing), or diamine oxidase; methylamine dehydrogenase; tryptophan tryptophylquinone enzymes; nitric-oxide synthase; b-fructofuranosidase, or invertase; monoamine oxidase, or amine oxidase; histidine decarboxylase; aldose reductase; catalase; formation of advanced glycosylation end products; adenosylmethionine decarboxylase; arginine deaminase; arginine kinase; aspartate aminotransferase; histamine N-methyltransferase.Пимагедин запасные части и сырье
Пимагедин поставщик
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