N',N'',N''',N''''-Pentaacetylchitopentaose

Химические свойства

White Solid

Использование

Studies have shown this compound to have anti tumor effects.

Методы производства

Cell density cultivation of recombinant Escherichia coli strains harboring the nodC gene (encoding chitooligosaccharide synthase) from Azorhizobium caulinodans has been previously described as a practical method for the preparation of gram-scale quantities of penta-N-acetyl-chitopentaose. We have now extended this method to the production of allylated derivative of penta-N-acetyl-chitopentaose by using allyl 2-acetamido-2-deoxy-β-d- glucopyranoside (2) as the initial acceptor for the synthesis of target pentaoside in vivo.

1. Chemo-enzymatic synthesis of allyl penta-N-acetyl-chitopentaose
2. Huang, Gang-Liang; Zhang, Da-Wei; Zhao, Hong-Juan; Zhang, Hou-Cheng; Wang, Peng-George - Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 7, p. 2042 - 2043