8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
- английское имя8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- CAS №51239-26-0
- CBNumberCB5369780
- ФормулаC16H14ClN5NaO7PS
- мольный вес509.79
- номер MDLMFCD00674888
- файл Mol51239-26-0.mol
химическое свойство
| температура хранения | -20°C |
| растворимость | H2O: 25 mg/mL |
| форма | powder |
| цвет | white |
| Растворимость в воде | H2O: 25mg/mL |
| UNSPSC Code | 41106305 |
| NACRES | NA.77 |
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt химические свойства, назначение, производство
Использование
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt has been used to activate GMP-dependent protein kinase (PKG) in vascular smooth muscle cells (VSMCs).Биохимия/физиол Действия
Membrane-permeable analog of cGMP that does not affect cGMP-regulated phosphodiesterase. A more potent cGMP analog than 8-Br-cGMP due to greater membrane permeability and a higher resistance to hydrolysis by phosphodiesterase. Used as a selective activator of cGMP dependent protein kinase (PKG). Found to be a very potent cyclic nucleotide-gated channel agonist.8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt поставщик
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