KU-60019
- русский язык имя
- английское имяKU-60019
- CAS №925701-49-1
- CBNumberCB52518276
- ФормулаC30H33N3O5S
- мольный вес547.66512
- номер MDLMFCD18384974
- файл Mol925701-49-1.mol
химическое свойство
| плотность | 1.314 |
| температура хранения | -20°C |
| растворимость | ≥27.4 mg/mL in DMSO; insoluble in H2O; ≥51.2 mg/mL in EtOH |
| форма | powder |
| цвет | white to beige |
| FDA UNII | IAN358A69K |
KU-60019 химические свойства, назначение, производство
Использование
KU-60019 has been used to block ataxia telangiectasia mutated (ATM), to study its association of with the regulation of H2AX (H2A histone family, member X) and apoptosis inducing factor (AIF)-mediated cell death.Биохимия/физиол Действия
KU-60019 is a potent inhitor of ATM (ataxia telangiectasia mutated) kinase, a member of phosphatidylinositol-3-kinase-related kinase family that is critical in regulating cell cycle checkpoints and DNA repair. KU-60019 has an IC50 value of 6.3 nM. KU-60019 radiosensitizes U1242 human glioma cells, and also blocks U1242 cell migration and invasion through matrigel.KU-60019 поставщик
| поставщик | телефон | страна | номенклатура продукции | благоприятные условия |
|---|---|---|---|---|
| 571-85586718 +8613336195806 |
China | 29798 | 60 | |
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China | 29889 | 58 | |
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China | 5738 | 58 | |
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China | 24295 | 58 | |
| +1-2135480471 +1-2135480471 |
China | 10522 | 58 | |
| +1-708-310-1919 +1-13798911105 |
United States | 6393 | 58 |