![ChemicalBook](https://m.chemicalbook.com/Scripts/New/img/logo.png)
![структурированное изображение](/CAS/20180808/GIF/925701-49-1.gif)
KU-60019
- русский язык имя
- английское имяKU-60019
- CAS №925701-49-1
- CBNumberCB52518276
- ФормулаC30H33N3O5S
- мольный вес547.66512
- номер MDLMFCD18384974
- файл Mol925701-49-1.mol
химическое свойство
плотность | 1.314 |
температура хранения | -20°C |
растворимость | ≥27.4 mg/mL in DMSO; insoluble in H2O; ≥51.2 mg/mL in EtOH |
форма | powder |
цвет | white to beige |
FDA UNII | IAN358A69K |
KU-60019 химические свойства, назначение, производство
Использование
KU-60019 has been used to block ataxia telangiectasia mutated (ATM), to study its association of with the regulation of H2AX (H2A histone family, member X) and apoptosis inducing factor (AIF)-mediated cell death.Биохимия/физиол Действия
KU-60019 is a potent inhitor of ATM (ataxia telangiectasia mutated) kinase, a member of phosphatidylinositol-3-kinase-related kinase family that is critical in regulating cell cycle checkpoints and DNA repair. KU-60019 has an IC50 value of 6.3 nM. KU-60019 radiosensitizes U1242 human glioma cells, and also blocks U1242 cell migration and invasion through matrigel.KU-60019 поставщик
поставщик | телефон | страна | номенклатура продукции | благоприятные условия |
---|---|---|---|---|
571-85586718 +8613336195806 |
China | 29798 | 60 | |
+undefined-21-51877795 | China | 32836 | 60 | |
+86-0371-86658258 +8613203830695 |
China | 29889 | 58 | |
86-13657291602 | CHINA | 22968 | 58 | |
+1-631-485-4226 | United States | 19553 | 58 | |
+8618523575427 | China | 49392 | 58 | |
+86-021-61551413 +8618813727289 |
China | 5738 | 58 | |
+86-29-89586680 +86-15129568250 |
China | 24295 | 58 | |
+1-2135480471 +1-2135480471 |
China | 10522 | 58 | |
+1-708-310-1919 +1-13798911105 |
United States | 6393 | 58 |