Винрозидин

Описание

Also obtained from Vinca rosea L., this alkaloid is dextrorotatory with [α]²⁵_D + 55.8° (CHCI3). There are two absorption maxima in the ultraviolet spectrum at 214 and 265 mfJ.. A crystalline O,O,N-triacetyl derivative has been prepared with m.p. 154-9°C (dec.); [α]²⁵_D + 12.6° (CHCl3). Two of the nitrogen atoms are tertiary, the others being present as an imino and a methylimino group respec? tively. The structure has been established from chemical

Использование

Antineoplastic.

использованная литература

Svoboda., Lloydia, 24, 173 (1961)
Structure:
Neuss, Huckstep, Cone., Tetrahedron Lett., 811 (1967)