simfibrate
- русский язык имя
- английское имяsimfibrate
- CAS №14929-11-4
- CBNumberCB4875031
- ФормулаC23H26Cl2O6
- мольный вес469.35
- EINECS238-998-7
- номер MDLMFCD00865760
- файл Mol14929-11-4.mol
химическое свойство
| Температура плавления | 51-53° |
| Температура кипения | bp0.03 197-200°; bp0.15 220-230° |
| плотность | 1.2623 (estimate) |
| FDA UNII | L2R75RQX26 |
| Код УВД | C10AB06 |
| Токсичность | LD50 in mice, rats (g/kg): 3.3-3.5; 7.3-8.0 orally (Nakanishi, J. Pharm. Soc. Japan) |
simfibrate химические свойства, назначение, производство
Создатель
Cholesorbin,Takeda,Japan,1971Производственный процесс
A mixture of 22 grams of α-(p-chlorophenoxy)isobutyric acid, 3.8 grams of 1,3-propanediol, 0.5 gram of p-toluenesulfonic acid and 150 ml of xylene was refluxed. When the theoretically calculated amount of water had been removed, the xylene solution was washed with dilute aqueous sodium bicarbonate and then the xylene was distilled off. The residue was distilled under reduced pressure to give 11 grams (47% yield) of 1,3-propanediol bis[α-(p-chlorophenoxy)isobutyrate] boiling at 197° to 200°C/0.03 mm Hg.Терапевтическая функция
Antihyperlipidemicsimfibrate запасные части и сырье
simfibrate поставщик
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