Далфопристин
- английское имяDalfopristin
- CAS №112362-50-2
- CBNumberCB31075198
- ФормулаC34H50N4O9S
- мольный вес690.85
- номер MDLMFCD00895414
- файл Mol112362-50-2.mol
химическое свойство
| Температура плавления | ~150° |
| Температура кипения | 940.5±65.0 °C(Predicted) |
| плотность | 1.27±0.1 g/cm3(Predicted) |
| температура хранения | Store at -20°C |
| растворимость | DMSO:113.0(Max Conc. mg/mL);163.57(Max Conc. mM) Ethanol:100.0(Max Conc. mg/mL);144.75(Max Conc. mM) |
| форма | Solid |
| пка | 13.18±0.70(Predicted) |
| цвет | White to yellow |
| FDA UNII | R9M4FJE48E |
| Банк данных об опасных веществах | 112362-50-2(Hazardous Substances Data) |
Далфопристин химические свойства, назначение, производство
Использование
Dalfopristin is a semi-synthetic analogue of ostreogyrcin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogyrcin, followed by oxidation to the sulphone. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Dalfopristin is used commercially in synergistic combination with quinupristin (70:30). There is little published data on the synthesis, biological or antibiotic activity of dalfopristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.Далфопристин поставщик
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