3,3',4,4'-TETRACHLOROBIPHENYL

Использование

3,3'',4,4''-Tetrachlorobiphenyl is a polychlorinated biphenyl (PCB) congeners.

Определение

ChEBI: A tetrachlorobiphenyl that is biphenyl in which the hydrogens at position 3 and 4 on each phenyl group are replaced by chlorines.

Профиль безопасности

Poison by ingestion. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-. See also POLYCHLORINATED BIPHENYLS.

Метаболический путь

When 3,4,3',4' -tetrachlorobiphenyl (TCB) is orally administered to rats, seven hydroxylated metabolites are identified in the rat feces. The major metabolites are 5-hydroxy-3,4,3',4' -TCB and 4-hydroxy-3,5,3',4' - TCB. One further metabolite isolated is an oxepin, existing in a state of equilibration with the 4',5' - epoxide of the major metabolite, 4-hydroxy-3,5,3',4' -TCB.