6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one
- русский язык имя
- английское имя6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one
- CAS №851067-56-6
- CBNumberCB02627155
- ФормулаC22H26BrN7O
- мольный вес484.39
- файл Mol851067-56-6.mol
химическое свойство
| Температура кипения | 682.2±65.0 °C(Predicted) |
| плотность | 1.495±0.06 g/cm3(Predicted) |
| растворимость | Aqueous Acid (Slightly), DMSO (Slightly, Heated), DMF (Slightly, Heated) |
| пка | 8.66±0.10(Predicted) |
| форма | Solid |
| цвет | Off-White to Yellow |
| FDA UNII | MGB9JX8TMP |
6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one химические свойства, назначение, производство
Использование
6-Desacetyl-6-Bromo Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.Also, it is derived from 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one (B682195), which is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one поставщик
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