(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]-propionic Acid Sesquihydrate

Химические свойства

White Crystalline Solid

Использование

A selective inhibitor of [3H]-AMPA binding in rat brain membranes. AMOA shows little affinity for [3H]-kainate binding sites or other sites on the NMDA receptor-channel complex, as represented by binding of [3H]-CPP, [3H]-gly or [3H]-MK-801. AMOA also selectively antagonizes AMPA-induced responses in rat cortical wedge preparations relative to kainate-, quisqualate- and NMDA-induced responses.