Side effects of Glycopyrrolate

Glycopyrronium bromide is a quaternary amine with similar anticholinergic actions to atropine but without central effects because it is a quaternary amine and does not cross the blood–brain barrier. It is used as an alternative to atropine during the reversal of neuromuscular blockade or as an antisialagogue during fibreoptic intubation. It is effective at a dose of 200μg i.m./i.v., with minimal central or cardiovascular effects.

Use

Glycopyrrolate is used in combination with other medications to treat ulcers in adults and children 12 years of age and older. Glycopyrrolate (Cuvposa) is used to reduce saliva and drooling in children between 3 and16 years of age that have certain medical conditions that cause drooling. Glycopyrrolate is in a class of medications called anticholinergics. It decreases stomach acid and saliva production by blocking the activity of a certain natural substance in the body.

How to use

Glycopyrrolate comes as a tablet and solution (liquid) to take by mouth. For the treatment of ulcers, the tablet is usually taken 2 or 3 times a day. To reduce saliva and drooling in children with certain medical conditions, the solution is usually taken 3 times a day. Take the solution on an empty stomach (at least 1 hour before or 2 hours after a meal). Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take glycopyrrolate exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using glycopyrrolate and call your doctor at once if you have:

severe constipation, severe stomach pain and bloating;

diarrhea (especially if you have a colostomy or ileostomy);

painful or difficult urination;

fast or pounding heartbeats, fluttering in your chest;

confusion, severe drowsiness;

eye pain, seeing halos around lights;

fever, shallow breathing, weak pulse, hot and red skin.

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