Lidocaine synthesis
Lidocaine also called lidopen, xylocaine, xylocard, is a prototype of antiarrhythmic drugs of subgroup IB, and is a sodium channel blocker (class 1B antiarrhythmic) that causes a depression of rapidly depolarizing tissue. It can be used as a local anesthetic and as an antiarrhythmic after heart attacks. It has also found use in asthma therapy (dispensed in nebulizers).
Lidocaine is usually administered intravenously for short-term therapy of ventricular extrasystole, tachycardia, especially in the severe phase of myocardial infarction, arrhythmia of natural cause, and for arrhythmia that can originate in the heart during surgical manipulations.
A method for preparing lidocaine: using 2,6-dimethylaniline and chloroacetic chloride as raw materials to prepare an intermediate, namely acetyl chloride-2,6-dimethylaniline, and using the prepared intermediate and diethylamine to react and obtain lidocaine, wherein acetone is used as solvent and carbonate is used as catalyst in thereaction process.
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Lastest Price from Lidocaine manufacturers
![137-58-6 Lidocaine](/ProductImageEN/2024-06/Small/4e087489-346c-4bcd-9a5f-45d3956fd3aa.jpg)
US $40.00-35.00/box2024-07-30
- CAS:
- 137-58-6
- Min. Order:
- 1box
- Purity:
- 99.9+
- Supply Ability:
- 2000box
![137-58-6 Lidocaine](/ProductImageEN/2024-06/Small/e3af4e36-6cf4-433f-8bb3-bb628b01c99e.jpg)
US $40.00-35.00/box2024-07-30
- CAS:
- 137-58-6
- Min. Order:
- 1box
- Purity:
- 99.9+
- Supply Ability:
- 20000box