托吡卡胺

Tropicamide
1508-75-4

询价 25Kg/Drum 起订

湖北更新日期：2020-11-10

九州通医药集团股份有限公司

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产品详情:

中文名称：: 托吡卡胺

英文名称：: Tropicamide

CAS号：: 1508-75-4

产品类别：: boshan

Tropicamide

Tropicamide structure	Common Name	Tropicamide
	CAS Number	1508-75-4	Molecular Weight	284.353
	Density	1.2±0.1 g/cm3	Boiling Point	492.8±45.0 °C at 760 mmHg
	Molecular Formula	C17H20N2O2	Melting Point	98 °C
	MSDS	ChineseUSA	Flash Point	251.8±28.7 °C
	Symbol	GHS07	Signal Word	Warning

Use of Tropicamide

Tropicamide is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist .Target: mAChRTropicamide is an antimuscarinic drug that produces short acting mydriasis (dilation of the pupil) and cycloplegia when applied as eye drops. It is used to allow better examination of the lens, vitreous humor, and retina. Due to its relatively short duration of effect (4-8 hours), it is typically used during eye examinations such as the dilated fundus examination, but it may also be used before or after eye surgery. Cycloplegic drops are often also used to treat anterior uveitis, decreasing risk of posterior synechiae and decreasing inflammation in the anterior chamber of the eye [1-3].

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> mAChR

Signaling Pathways >> Neuronal Signaling >> mAChR

Research Areas >> Neurological Disease

References

[1]. Lazareno, S., N.J. Buckley, and F.F. Roberts, Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. Mol Pharmacol, 1990. 38(6): p. 805-15.

[2]. Hernandez, M., et al., Different muscarinic receptor subtypes mediating the phasic activity and basal tone of pig isolated intravesical ureter. Br J Pharmacol, 1993. 110(4): p. 1413-20.

Density	1.2±0.1 g/cm3
Boiling Point	492.8±45.0 °C at 760 mmHg
Melting Point	98 °C
Molecular Formula	C17H20N2O2
Molecular Weight	284.353
Flash Point	251.8±28.7 °C
Exact Mass	284.152466
PSA	53.43000
LogP	1.15
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.586
Storage condition	2-8°C
Water Solubility	45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.3 mg/mL

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302 + H312 + H332-H315-H317-H319-H335
Precautionary Statements	P261-P280-P301 + P312 + P330-P305 + P351 + P338
Hazard Codes	Xn:Harmful
Risk Phrases	R20/21/22;R36/37/38;R42/43
Safety Phrases	S22-S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	CY1487860
HS Code	2933399090

4-(Ethylaminome...

CAS#:33403-97-3

Tropicamide

CAS#:1508-75-4

Literature: DE960634 , ;

Acetyltropylic ...

CAS#:14510-37-3

4-(Ethylaminome...

CAS#:33403-97-3

Tropicamide

CAS#:1508-75-4

Literature: DE960634 , ;

Precursor 2
CAS#:33403-97-3 4-(Ethylaminome... CAS#:14510-37-3 Acetyltropylic ...
DownStream 4
CAS#:492-38-6 2-Phenylacrylic acid CAS#:529-64-6 Tropic acid CAS#:57322-50-6 n-ethyl-n-(4-pi...

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Tropicamide;CAS 1508-75-4;

公司简介

九州通是一家以西药、中药、器械为主要经营产品，以医疗机构、批发企业、零售药店为主要客户对象，并为客户提供信息、物流等各项增值服务的大型企业集团。公司立足于医药健康行业，是中国医药商业领域具有全国性网络的少数几家企业之一，于2010年11月2日在上海证券交易所挂牌上市（股票简称：九州通，证券代码：600998），公司连续多年位列中国医药商业企业第四位，领跑中国民营医药商业企业，2020年位列《财富》（中文版）500强第100位。九州通成立于1999年3月，总部位于湖北省武汉市。截止2020年9月30日，公司注册资本18.78亿元，总资产787.17亿元。实现营业收入803.20亿元，净利润21.41亿元，分别较上年同期增长9.46%和110.23％。扣除非经常性损益后归属于上市公司股东的净利润为12.52亿元，较上年同期增长45.12%。2019年公司实现营业收入994.97亿元，归属于上市公司股东的净利润17.81亿元，分别较上年同期增长14.19%和28.96%。员工两万五千余人。直营和加盟零售连锁药店1074家。

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经营模式	贸易,工厂
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