BMVC-8C3O

BMVC-8C3O is a DNA G-quadruplexe (G4) ligand which can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s^[1].

BMVC-8C3O induces topological conversion of Tel23 from a hybrid-I G4 to a parallel G4 in K+solution^[1].
BMVC-8C3O binding can induce topological changes of different non-parallel human telomeric G4s into the same parallel topology^[1].

1042.61

C₄₂H₅₃I₃N₄O₃

1301708-12-2

C[N+]1(CCOCCOCCOCCN2C3=C(C4=C2C=CC(/C=C/C5=CC=[N+](C)C=C5)=C4)C=C(/C=C/C6=CC=[N+](C)C=C6)C=C3)CCCCC1.[I-].[I-].[I-]

Room temperature in continental US; may vary elsewhere.