ANTI-BCL-2抗体

品牌:Leading Biology     

货号:LBP71603

产品分类:多克隆抗体     

产品概述:Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

浓度:Rabbit anti Human Bcl-2 antinody recognizes human Bcl-2, a 239 amino acid ~25 kDa integral outer mitochondrial membrane protein that blocks apoptotic death in a variety of cell systems. Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability. It inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (apaf-1). Bcl-2 is antiproliferative by facilitating G0entry.Constitutive expression of Bcl-2 is thought to be the cause of follicular lymphoma, also known as type II chronic lymphatic leukaemia. Bcl-2 mutations have also been found in Non-Hodgkin Lymphomas.

纯度Rabbit

储存条件Human

储存溶液Apoptosis regulator Bcl-2, BCL2