Threonine Deaminase,中文名为苏氨酸脱氨酶,催化苏氨酸脱氨,生成2-酮丁酸和氨。本产品为大肠杆菌表达的苏氨酸脱氨酶,并经简单纯化获得的可以确保达到一定酶活力的粗酶液。
由于本产品需新鲜制备,确认订购后约6个工作日才可以发货。个别情况首次制备出现问题,发货时间会顺延。
本产品可以提供十公斤、百公斤乃至吨级的粗酶液,如有需求请联系康朗。
Threonine ammonia-lyase, also commonly referred to as threonine deaminase or threonine dehydratase, is an enzyme responsible for catalyzing the conversion of L-threonine into alpha-ketobutyrate and ammonia. Alpha-ketobutyrate can be converted into L-isoleucine, so threonine ammonia-lyase functions as a key enzyme in BCAA synthesis.It employs a pyridoxal-5’-phosphate cofactor, similar to many enzymes involved in amino acid metabolism. It is found in bacteria, yeast, and plants, though most research to date has focused on forms of the enzyme in bacteria. This enzyme was one of the first in which negative feedback inhibition by the end product of a metabolic pathway was directly observed and studied.The enzyme serves as an excellent example of the regulatory strategies used in amino acid homeostasis. This product with the indicated enzyme activity was briefly purified from engineered E.coli. 产品详细信息见下表: