Recombinant Murine Uteroglobin

Name

Recombinant Murine Uteroglobin (Recombinant Murine Uteroglobin; rMuUteroglobin)； Recombinant Mouse Uteroglobin ; 重组小鼠宫珠蛋白

Synonyms

Blastokinin; CC10; CC16; CCPBP; CCSP; Clara; PCB-BP; SCGB1A1; UGB; blastokinin; CC10Urine protein 1; CC16; CCSPCCPBP; Clara cell phospholipid-binding protein; Clara cells 10 kDa secretory protein; Secretoglobin family 1A member 1; secretoglobin, family 1A, member 1 (uteroglobin); UGBUP-1; UP1; Urinary protein 1; uteroglobin

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0μg/ml, corresponding to a specific activity of >200IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 0.1EU/μg of rMuUteroglobin as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Others

Background

Uteroglobin, also known as secretoglobin family 1A member 1 (SCGB1A1), is encoded by thek SCGB1A1 gene. Uteroglobin is the founding protein of the secretoglobin family, whose members are small, secreted, disulfide-bridged dimeric proteins found in mammals only. Uteroglobin is specifically expressed in clara cells in the lungs. It is multifunctional and found in various tissues in various names such as: uteroglobin (UG, UGB), uteroglobin-like antigen (UGL), blastokinin, clara cell secretory protein (CCSP), clara cell 16 kD protein (17 in rat/mice), clara Cell-Specific 10 kD protein (CC10), human protein 1, urine protein 1 (UP-1), polychlorinated biphenyl-binding protein (PCB-BP), human clara cell phospholipid-binding protein (hCCPBP), secretoglobin 1A member 1 (SCGB1A1). Its putative functions include immunomodulation, progesterone binding (weak in some animals, especially weak in humans), phospholipase A2 inhibitor etc. Murine uteroglobin shares 54% amino acid sequence identity with human uteroglobin.

Amino Acid Sequence

DICPGFLQVL EALLMESESG YVASLKPFNP GSDLQNAGTQ LKRLVDTLPQ ETRINIMKLT EKILTSPLCK QDLRF

产品编号

产品名称

包装

KL7352-10μg

Recombinant Murine Uteroglobin

10μg

KL7352-50μg

Recombinant Murine Uteroglobin

50μg

KL7352-100μg

Recombinant Murine Uteroglobin

100μg

KL7352-1mg

Recombinant Murine Uteroglobin

1mg

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说明书

1份