Recombinant Human Apo-SAA1 (Recombinant Human Apolipoprotein-Serum Amyloid A1; rHuApo-SAA1);重组人血清淀粉样蛋白A1
Synonyms
MGC111216; PIG4; SAA; SAA2; serum amyloid A protein; serum amyloid A1; TP53I4; tumor protein p53 inducible protein 4; PIG4; SAA1
Purity
>98% by SDS-PAGE and HPLC analyses.
Biological Activity
Fully biologically active when compared to standard. The biological activity determined by a chemoattract bioassay using human monocytes is in a concentration range of 10-100ng/ml.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in 20mM Tris-HCl, pH9.0, 150mM NaCl.
Endotoxin
N/A
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
Category
Others
Background
Serum amyloid A-1 protein which belongs to the SAA family is encoded by the SAA1 gene in humans. It is expressed by the liver and secreted in plasma. Serum amyloid A-1 is the major acute phase reactant and apolipoprotein of the HDL complex. Elevated serum SAA1 protein levels may be associated with lung cancer. The level of Apo-SAA1, normally 1-5μg/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL Apo-lipoprotein. Recombinant human Apo-SAA1 is an 11.7kDa protein containing 104 amino acid residues.