Less than 1EU/μg of rHuBcl-w as determined by LAL method.
Reconstitution
N/A
Category
Others
Background
Bcl-w, also named as BCL2L2, belongs to the Bcl-2 family and is encoded by the BCL2L2 gene in human. Bcl-w is expressed in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands, and moderate levels in thymus, ovary and small intestine. It is also expressed in cell lines of myeloid, fibroblast and epithelial origin. Bcl-w is an anti-apoptotic (pro-survival) protein that reduces cell apoptosis under cytotoxic conditions. Mature human Bcl-w shares 98%-99% amino acid sequence identity with murine, bovine, canine Bcl-w.